Houston shortstop Jeremy Peña was not in the lineup Saturday but was feeling better after leaving the Astros’ victory over the Chicago Cubs on Friday night in the fifth inning because of rib soreness,

Major League Baseball Astros SS Jeremy Peña leaves game vs. Cubs due to left rib soreness after being hit by pitch. Houston Astros shortstop Jeremy Peña left Friday night’s ga

Astros shortstop Jeremy Pena was hit by a pitch on his left side and was forced to leave Friday night's 7-4 win over the Cubs with left rib soreness.

Houston powered to a 7-4 victory last night, sparked by three-run homers from Cam Smith and Yainer Diaz, and my Cubs vs Astros predictions signal more home cooking here in a prime-time slot. Read on for my free MLB picks and betting angles ahead of this marquee June 28 battle.

Pregame analysis and predictions of the Chicago Cubs vs. Houston Astros MLB game to be played on June 27, 2025 on ESPN.

Chicago Cubs (48-34, first in the NL Central) vs. Houston Astros (49-33, first in the AL West) Houston; Saturday, 7:15 p.m. EDT. PITCHING PROBABLES: Cubs: Colin Rea (4-3, 4.42 ERA